Sex-related differences in atrophy and lesion load in multiple sclerosis patients

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[Sex-related differences in atrophy and lesion load in multiple sclerosis patients].

INTRODUCTION Previous studies showed gender-associated clinical and MRI differences in multiple sclerosis (MS) evolution. However, only few studies were done with non conventional MRI techniques and no one was done in a South American MS population. The aim of this study was to investigate gender differences according to nonconventional MRI measures in patients with MS from Buenos Aires, Argent...

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Focal cortical atrophy in multiple sclerosis: relation to lesion load and disability.

Multiple sclerosis (MS) is thought to predominantly affect white matter (WM). Recently, however, loss of cortical gray matter has also been described. Little is known about the cause of cortical atrophy in MS, whether it occurs early in the disease course, and whether it affects all cortical regions equally or if there is a preferential pattern of focal cortical atrophy. An automated method was...

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Sex Differences in Depression in Patients with Multiple Sclerosis

Multiple Sclerosis (MS) is a demyelinating disorder of the central nervous system. Approximately 50% of MS patients experience clinical depression at some point during their lifetime, a rate that far exceeds what is found in the general population. This study examined sex differences in depression in 80 female and 17 male MS patients. The following four inventories for measuring depression were...

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Impairment of visuospatial/visuoconstructional skills in multiple sclerosis patients: the correlation with regional lesion load and subcortical atrophy.

INTRODUCTION About 20% to 26% of patients with multiple sclerosis (MS) show alterations in visuospatial/visuoconstructive (VS-VC) skills even though temporo-parieto-occipital impairment is a frequent finding in magnetic resonance imaging. No studies have specifically analysed the relationship between these functions and lesion volume (LV) in these specific brain areas. OBJECTIVE To evaluate t...

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P-137: Sex Hormones Abnormalities and Female Sexual Dysfunction in Multiple Sclerosis Patients

Background: Multiple sclerosis (MS) is the most common cause of progressive neurological disability in young adults who may be sexually active. MS patients experience high levels of sexual dysfunction with hypoactive sexual behavior and abnormalities in hypothalamus- pituitary-gonad (HPG) axis. In the present study, we aimed to evaluate the correlation between serum levels of sex hormones durin...

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ژورنال

عنوان ژورنال: Neurología (English Edition)

سال: 2013

ISSN: 2173-5808

DOI: 10.1016/j.nrleng.2012.10.003